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There may be new hope for arthritis relief

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Genetic clue to arthritic relief discovered

Osteoarthritis, the most common type of arthritis, is a condition that creates a gradual loss of protective cartilage around the joint, causing the bones to grind, develop spurs and become misshapen. These changes also create pain, stiffness and general lack of flexibility. The primary mechanisms of arthritis relief are lifestyle changes and pain relievers. However, scientists have recently discovered a possible genetic base for cartilage destruction. Changing the way that gene functions may reduce or eliminate the cartilage destruction process that comes from osteoarthritis.

Researchers investigating methods of arthritis relief know that cartilage contains a specific substance called aggrecan that acts as a shock absorber. That substance is lost in the arthritic process; the loss occurs by the action of a specific enzyme. US and Australian researchers discovered the specific gene responsible for the cartilage-eating enzyme. If they can now figure out how to block the action of that enzyme, arthritis relief could on the way.

In the meantime, you should follow the best current thinking for obtaining arthritis relief for your osteoarthritis. That approach includes lifestyle changes and pain reducers.

You can gain arthritis relief as well as reducing the damage to your body from arthritis by getting to and maintaining your ideal weight. Extra body weight adds extra burden on many joints and accelerates the process of cartilage destruction.

Some arthritis relief can also be gained by taking pain relief and anti-inflammatory drugs. Doctors often first recommend a pain reliever called acetaminophen for people who have osteoarthritis. Acetaminophen is the active ingredient in many over-the-counter pain relievers. Acetaminophen does not cause stomach irritation like some other pain relievers, such as aspirin. Acetaminophen is more effective when it is used regularly than when it is used only occasionally.

Nonsteroidal anti-inflammatory drugs are also used for arthritis relief. The most frequently used NSAIDs are aspirin, ibuprofen, and naproxen. Like acetaminophen, these drugs relieve pain in the affected joints. They may reduce inflammation as well, which is why they are called anti-inflammatory medications. Many NSAIDs are available over the counter, but stronger ones require a prescription from a doctor.

Corticosteroids may be used for arthritis relief as well. Corticosteroids are man-made substances that are related to cortisone, a naturally occurring hormone that your body makes. Corticosteroids are used to reduce pain and inflammation (redness, warmth, and swelling) and can be injected directly into joints.

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